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| First Name: | William | | Last Name: | Grant | | Title: | Dr. | | Advanced Degrees: | Ph.D. | | Affiliation: | Sunlight, Nutrition and Health Research Center | | Department: | Independent researcher | | Street Address 1: | 2107 Van Ness Avenue | | Street Address 2: | Suite 403B | | City: | San Francisco | | State/Province: | CA | | Zip/Postal Code: | 94108-2529 | Country/Territory: | U.S.A. | | Phone: | 415-776-5274 | | Fax: | 4150776-5270 | | Email Address: |  |
Disclosure:
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Member reports no financial or other potential conflicts of interest. [Last Modified: 11 April 2004]
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View all comments by William Grant
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Alzheimer Disease, Aging Process, Neurodevelopmental Disorders (Down syndrome, etc.), Neuromuscular Disorders (ALS, etc.)
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Ph.D. in physics (UC Berkeley)
Published first paper linking diet to Alzheimer's
disease.
Continue to apply the ecologic approach to the
study of Alzheimer's, cancer, etc.
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Grant WB. Dietary links to Alzheimer's disease. Alz Dis Rev 1997;2:42-55
http://www.mc.uky.edu/adreview/default.htm
Grant WB. The APOE-epsilon4 allele and Alzheimer disease among African Americans, Hispanics, and Whites, JAMA, letter, Nov. 18, 1998;280:162-163.
Grant WB. Aluminum accumulates in body with high-acid diet, Townsend Letter for Doctors and Patients, June 1999;191:92.
Grant WB. Dietary links to Alzheimer's disease: 1999 update, J Alz Dis 1(4,5), 197-201, 1999. (Case Western Reserve University), (http://www.j-alz.com/numbers4-5.html)
Grant WB. Fish consumption, cancer, and Alzheimer disease, Am J Clin Nutr, letter, 2000 Feb;71:599.
http://www.ajcn.org/cgi/content/full/71/2/599
Grant WB. Incidence of dementia and Alzheimer disease in Nigeria and the United States, JAMA, May 16, 2001;285:2448-9. http://jama.ama-assn.org/issues/current/ffull/jlt0516-4.html
Grant WB, Campbell A, Itzhaki RF, Savory J, The significance of environmental factors in the etiology of Alzheimer's disease, J Alz Dis 4(3), Debates from Challenging Views of Alzheimer Disease, 2002;4:179-189.
*Grant WB. Diet and risk of dementia: Does fat matter? The Rotterdam Study. Neurology. 2003;60:2020-1.
*Grant WB. Obesity and Alzheimer disease: roles of diet and genetics. Arch Intern Med. 2004;164:109-10.
*Grant WB. Year 2000 prevalence of Alzheimer’s disease in the U.S., Arch. Neurol. in press, May 2004.
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G. J. Petot et al., Interactions of APOE genotype and dietary fat, Metabolism 2003;52:279-81.
Barberger-Gateau P, Letenneur L, Deschamps V, Pérès K, Jean-François Dartigues JF, Renaud S. Fish, meat, and risk of dementia: cohort study. BMJ 2002;325:932-3.
Luchsinger JA, Tang MX, Shea S, Mayeux R. Caloric intake and the risk of Alzheimer disease. Arch Neurol. 2002;59:1258-63.
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Dietary and lifestyle links to Alzheimer's disease. |
Diet and genetics interacting to give rise to much of AD. |
More epi studies, perhaps controlled double blind, but I think that well designed epi studies could be used to make a strong case for the interactions, as has been done recently. |
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